Office 2019 remain same major version 16 as predecessor Office 2016, therefore it is second perpetual release of Office 16. Some features that had previously been restricted to Office 365 subscribers are available in this release. It was unveiled on Apfor Windows 10 and Jfor macOS, and launched on September 24, 2018. It replaces Office 2016 and was replaced by Office 2021 on October 5, 2021. Microsoft Office 2019 (Second perpetual release of Office 16) is a version of Microsoft Office for both Windows and Mac.

Proofing only (11): Hausa, Igbo, isiXhosa, isiZulu, Kinyarwanda, Pashto, Romansh, Sesotho sa Leboa, Setswana, Wolof, Yoruba.

Partial (51): Afrikaans, Albanian, Amharic, Armenian, Assamese, Azerbaijani (Latin), Bangla (Bangladesh), Bangla (Bengali India), Basque (Basque), Belarusian, Bosnian (Latin), Catalan, Dari, Filipino, Galician, Georgian, Gujarati, Icelandic, Irish, Kannada, Khmer, KiSwahili, Konkani, Kyrgyz, Luxembourgish, Macedonian (Republic of Macedonia), Malayalam, Maltese, Maori, Marathi, Mongolian (Cyrillic), Nepali, Norwegian Nynorsk, Odia, Persian (Farsi), Punjabi (Gurmukhi), Quechua, Scottish Gaelic, Serbian (Cyrillic, Bosnia & Herzegovina), Serbian (Cyrillic, Serbia), Sindhi (Arabic), Sinhala, Tamil, Tatar (Cyrillic), Telugu, Turkmen (Latin), Urdu, Uyghur, Uzbek (Latin), Valencian, Welsh.

Full (40): English, Arabic, Bulgarian, Chinese (Simplified), Chinese (Traditional), Croatian, Czech, Danish, Dutch, Estonian, Finnish, French, German, Greek, Hebrew, Hindi, Hungarian, Indonesian, Italian, Japanese, Kazakh, Korean, Latvian, Lithuanian, Malay (Latin), Norwegian Bokmål, Polish, Portuguese (Brazil), Portuguese (Portugal), Romanian, Russian, Serbian (Latin, Serbia), Slovak, Slovenian, Spanish, Swedish, Thai, Turkish, Ukrainian, Vietnamese.

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